Cream Manufacturing

WHO-GMP certified cream manufacturing company in India, producing pharmaceutical creams and ointments for dermatological, antifungal, and cosmetic brands.

Product Name	Composition	Class
Footnut Cream	Urea 10.0%w/w + Liquid Paraffin 9.0%w/w + Cetostearyl Alcohol 6.33%w/w + Glycerin 5.0%w/w + Shea Butter 5.0%w/w + Propylene Glycol 5.0% + Stearyl Alcohol 3.0%w/w + Cetomacrogol 1000 2.5%w/w + Dimethicone 1.0%w/w + Glyceryl Monostearate 1.0%w/w + Sodium Lauryl Sulphate 1.0%w/w + Allantoin 0.2%w/w + Methylparaben 0.1%w/w + Perfume 0.1%w/w + Propylparaben 0.05% + Purified Water Q.s. to 100%	Cardiac & Diabetic, Creams, NSAIDs / Antirheumatoid / Antispasmodic / Muscle Relaxants	Details
Fungazole-B Cream	Clotrimazole l.0% + Beclomethasone Dipropionate 0.025%	Creams	Details
Fusac Cream	Fusidic acid 2.0% Cream	Creams	Details
Fusidic Acid 2% + Mometasone Furoate 0.1% Cream Manufacturer	Fusidic acid 2.0% + Mometasone 0.1% cream	Creams	Details
Itroderm Cream	Itraconazole 1%+ Ofloxacin IP 0.75%+ Ornidazole ip 2.0%+ Clobetasol Propionate USP 0.05%w/w	Creams	Details
Le'Touch Facewash	Salicylic Acid, Triclosan, Aloe Vera extract, Glycerin, Vitamin E Beads, Carbomer, Cocamidopropyl Betaine, Sodium Lauryl Ether Sulphate, Disodium ete, Glycolic Acid, DM Aqua & Fragrance.	Creams	Details
Luliconazole Cream Manufacturer	Lulliconazole 1% w/w	Creams	Details
Moisty Cream	White Soft Paraffin 13.2 %+ Liquid paraffin 10.2%	Creams	Details
Terbiflox Cream	Ofloxacin 0.75% w/w + Clobetasol Propionate 0.05% w/w + Miconazole Nitrate 2% w/w + Terbinafine HCL 1.00% w/w + Dexpanthenol 0.05% w/w + Methyl Paraben 0.2% w/w + Propyl Paraben 0.02% w/w	Creams	Details

Comprehensive Pharmaceutical Cream Manufacturing

Delwis Healthcare is a WHO-GMP certified cream manufacturing company in India, producing pharmaceutical creams and ointments for dermatological, antifungal, and cosmetic applications. Manufacturing runs through controlled emulsification and validated homogenization, so texture, viscosity, and stability stay consistent from the first batch to the thousandth.

As a third party cream manufacturer, we take formulations from development through commercial-scale production as part of our broader CMO manufacturing capability — the same infrastructure that supports our tablet, capsule, and injectable lines.

Types of Creams & Ointments We Manufacture

Our product range already spans several formulation categories — antifungal and antibacterial creams (Fusidic Acid & Mometasone Furoate Cream, Luliconazole, Terbiflox), moisturizing and barrier creams (Moisty, Footnut), and cosmetic formulations like Le'Touch Facewash. This breadth reflects what we manufacture as a GMP certified antifungal cream manufacturer in India, alongside general skin cream and cosmetic cream production.

For brands that need both dosage forms under one roof, our ointment contract manufacturing runs on the same validated lines, so a single product range spanning creams and ointments doesn't require two separate manufacturing partners.

Our Cream Manufacturing Process

The cream manufacturing process at Delwis follows a validated sequence under WHO-GMP conditions:

1. Phase Preparation—Oil-phase and water-phase ingredients are weighed and heated separately to their specified temperatures.

2. Emulsification—The two phases are combined under controlled temperature and mechanical shear, forming the oil-in-water or water-in-oil emulsion that defines the cream's texture.

3. Homogenization—The emulsion is passed through homogenization to break down droplet size, giving the finished product a smooth, uniform consistency.

4. Cooling & Active Addition—Once cooled to the appropriate range, heat-sensitive actives (antifungals, antibiotics, corticosteroids) are incorporated without degrading potency.

5. In-Process & Finished Testing—Viscosity, pH, microbial limits, and active content are tested against approved specs before release.

6. Filling—Product moves into tube or jar filling under controlled, contamination-free conditions.

This same flow applies whether the batch is a face cream, an antifungal cream, or a cosmetic formulation — only the active ingredients and phase composition change. A one-page flow chart version of this process is available on request for brands doing internal formulation review.

Difference Between Cream vs. Ointment vs. Lotion

Brands choosing a dosage form for a new dermatological product often ask about the difference between cream and ointment. The distinction comes down to the oil-to-water ratio: creams are roughly balanced emulsions (oil-in-water or water-in-oil, depending on formulation goals), while ointments are predominantly oil-based, giving them a heavier, more occlusive finish that sits longer on the skin.

Lotions sit at the other end of that spectrum — the difference between cream and lotion is mainly water content, with lotions carrying more water and less oil, making them thinner and faster-absorbing. Comparing cream vs lotion vs ointment side by side: ointments offer the strongest barrier and longest contact time, creams balance absorption with moisturizing effect, and lotions spread easiest over larger skin areas.

Formulation-wise, this is a question of oil in water vs water in oil cream base selection — the choice affects not just texture but also how well an active ingredient releases from the base. Within pharmaceutics, there are several standard types of cream base (absorption bases, emulsifying bases, water-soluble bases), and base selection is one of the first decisions we work through with a brand during formulation.

Quality Control for Cream & Ointment Formulations

Semi-solid formulations carry a failure mode solid dosage forms don't: phase separation. If the oil and water phases aren't emulsified and cooled correctly, a batch can look fine on release and then split in the tube months later. We control for this at every stage — phase temperature matching before emulsification, shear rate control during homogenization, and accelerated stability testing before a formulation ever reaches commercial scale.

Phase-matched heating and controlled-shear emulsification for every batch
Viscosity and pH testing at multiple in-process checkpoints, not just at release
Microbial limit testing suited to water-based formulations, which carry different contamination risk than dry dosage forms
Accelerated stability data generated before scale-up, so shelf-life issues surface in weeks, not after a brand has already gone to market

Our Manufacturing Approach: From Base Selection to Scale-Up

A cream or ointment project starts with the base — absorption base, emulsifying base, or water-soluble base — chosen against how the active ingredient needs to release and how the finished product should feel on skin. From there we move through pilot batching, stability confirmation, and scale-up, with the same base and process carried through so the commercial batch performs identically to what was approved in trial.

Batch sizes flex from small pilot runs to full commercial volumes without re-validating the process each time

Formulation and packaging decisions are made together, since tube or jar choice affects both stability and shelf appeal

Production scheduling is built around consistent supply, not one-off runs

Support Services Beyond the Manufacturing Line

Getting a cream formulation right doesn't end when the batch passes release testing — most brands still need help getting it into market.

Regulatory Documentation for Submission

We prepare the dossier-level documentation creams and ointments need for domestic approval or export clearance, so a brand isn't assembling that paperwork from scratch.

Shelf-Life & Stability Testing

Because emulsions are more prone to degrading over time than tablets or capsules, we run real-time and accelerated stability studies specifically to confirm how long a formulation holds before it's finalized for market.

Tube and Jar Filling

Filling is precision-controlled and tamper-evident, but we also account for how the product looks and handles once it's on a shelf or in a clinic — not just that it's sealed correctly.

Why Brands Choose Delwis for Cream Manufacturing

Brands don't choose a cream manufacturing partner the same way they'd choose a tablet manufacturer — texture, absorption feel, and formulation base matter as much as the active ingredient. That's the specific expertise we bring:

Formulation know-how across antifungal, antibacterial, cosmetic, and anti-aging cream categories — not a single-category specialization

Emulsification and homogenization systems built for semi-solid production specifically, not adapted from a solid-dosage line

A base-selection process worked out with the brand upfront, since the wrong base can undermine an otherwise good formulation

Documentation and stability data ready ahead of regulatory submission, not assembled after the fact

Capacity that scales from a first pilot batch to full commercial volume without moving to a different production line

Brands We Partner With for Cream Manufacturing

Dermatology-focused pharmaceutical brands adding cream or ointment SKUs to an existing range

Our Ideal Partners

Cosmetic and personal care companies needing a validated, GMP-compliant production partner

Brands entering the antifungal or anti-aging category for the first time and needing formulation guidance, not just production

Companies exporting to markets that require WHO-GMP documentation for semi-solid dosage forms

Start Your Cream Manufacturing Project

If you are looking for a reliable partner for anti aging cream or face cream production through compliant third party pharmaceutical manufacturing, Delwis Healthcare is ready to support your CMO requirements.

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FAQs

Below are common questions from pharmaceutical companies evaluating our CMO and third party pharmaceutical manufacturing capabilities for cream formulations.

Yes, our cream manufacturing facilities operate under WHO-GMP guidelines with validated emulsification, homogenization, and filling systems supported by comprehensive quality documentation.